Scientists Launch ‘Covid Reinfection’ Trial On Young, Healthy Volunteers In UK

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Covid trials

As part of a new UK study, scientists plan to attempt to reinfect young, healthy volunteers who have recovered from covid-19.

The volunteers will be deliberately exposed to covid for a second time to see how the immune system reacts.

The study, which has received ethics approval, is due to start in the next few weeks and will recruit 90 people aged 18-30.

The Evening Standard reports: Researchers at the University of Oxford have launched what is known as a “human challenge” trial to look at what happens when someone who has recovered from Covid-19 infection is then re-exposed to the virus.

They will aim to determine what dose of virus is needed to re-infect after natural infection, how the immune system responds, and what this may mean for developing protective immunity against the disease.

The study, which is funded by the Wellcome Trust and is expected to start this month after receiving ethics approval, will recruit people aged 18-30 who have previously been naturally infected with Covid-19.

They will be re-exposed to the virus in a safe and controlled environment while a team of researchers monitor their health.

Human challenge studies have played a key role in furthering the development of treatments for diseases such as malaria, TB, typhoid, cholera and flu.

A similar study is ongoing in the UK where volunteers are being infected with coronavirus to test vaccines and treatments.

“As well as enhancing our basic understanding, this may help us to design tests that can accurately predict whether people are protected”

Helen McShane, professor of vaccinology at the department of paediatrics, University of Oxford and chief investigator on the study, said: “Challenge studies tell us things that other studies cannot because, unlike natural infection, they are tightly controlled.

“When we re-infect these participants, we will know exactly how their immune system has reacted to the first Covid infection, exactly when the second infection occurs, and exactly how much virus they got.

“As well as enhancing our basic understanding, this may help us to design tests that can accurately predict whether people are protected.”

While Covid-19 infections have been rare, recent research suggests prior infection may not fully protect young people against reinfection.

The observational study, published in the Lancet involving US Marine Corps members mostly aged 18-20, showed that between May and November 2020, around 10% of participants who had previously caught coronavirus became re-infected.

The Oxford study will take phase in two phases.

The first phase, involving 64 healthy volunteers, will aim to establish the lowest dose of virus which can take hold and start replicating.

Once the dosing amount is established, it will be used to infect participants in the second phase of the study, which is expected to start in the summer.

The information from this work will allow us to design better vaccines and treatments, and also to understand if people are protected after having Covid, and for how long

Prof McShane said: “We will measure the immune response at several time points after infection so we can understand what immune response is generated by the virus.

“A challenge study allows us to make these measurements very precisely because we know exactly when someone is infected.

“The information from this work will allow us to design better vaccines and treatments, and also to understand if people are protected after having Covid, and for how long.”

Prof McShane virus used in the study will be the original strain from Wuhan China “because that is the strain that we have most clinical, immunological (and) virological data on” but added discussions are under way to include one of the new coronavirus variants.

24 Comments

    • Yeah, this is not what they say it is. I think these people are using different strains to find out which one would be most effective at wiping out the vast majority of the population of a specific country.

      • Howdy Salacious B Crumb. Yes, actually that is the intent of much of the government sponsored viral research done in the world. They alter known viruses and intentionally make them more lethal in order to come up with ways to counter the more dangerous strains. Officially, that sounds very noble. And yes, that is also the basic principle of biological warfare. Since the UN outlawed biological warfare in 1969, the US stopped their research. Many people have been clamoring for a defensive bio research program for years, given the number of hostile countries who have ignored the UN ban. The counter argument has always been that if we were attacked with a bio weapon, we would respond with nuclear war. But that argument has always been hollow because the “intent” of the country releasing the bio weapon would have to be proven. For example, if a bio weapon was released and it killed half a million Americans, all the country that released the weapon would have to do is say, “oops, we are sorry”; and the threat of a nuclear retaliation would disappear. If you think about it, China hasn’t even bothered to say they are sorry. So maybe a defensive bio warfare program should be started up again. Although it hasn’t yet been pointed out in the press, this virus clearly is more lethal to European people. If you added up all the reported deaths in Asia; including India, the Middle East, China, and Japan; you would still be 100,000 less that the reported deaths in just the United States. And India and China alone have populations exceeding 2.7 billion people. Proportionately, 400,000 deaths between just those two countries wouldn’t even show up in their census figures. Since we cannot stop other countries from this type of bio research, we should be working on defending ourselves from their bio research.

        • They would have died anyway Most of the death certs are fudge .Look at the death rate pre covid and after .

          • Howdy Annonymous. Are the death certifications in Europe and South America also fake? But to your point, I fully plan to professionally analyze the CDC death information for 2020 and 2021 when it becomes available. The final 2020 CDC death data will be available for analysis by June 2022, and the final 2021 CDC data will be available for analysis by June 2023. The analysis will require incorporating the growing number of deaths from the previous 5 years and making a forecast of expected deaths for 2020 and 2021. Then I will have to determine if the reported deaths are mathematically “significantly” higher than the forecast. If it is, then by how many deaths. That will give me a basis to determine how many Covid related deaths would have died anyway from normal causes. If there is no mathematically significant increase in deaths, from my forecast, then I will know that too. Either way, I will share my information. But until I can make that analysis, I will not dismiss the published data.

        • They outlaw things so they go underground and the public then have no knowledge That’s why .They go black market and so become completely criminal operations where the best profits can be made

          • Howdy Annonymous. So what you are saying is that company X pays off several high level Democrat politicians to outlaw bio weapon research in the US, just so the company X can secretly make big profits through criminal operations. Are you thinking what you are saying through? Any American company willing to do bio warfare research for a country willing to pay them lots of money, only has to move their lab to that foreign country. There would be no reason to spend the money to pay off Democrat politicians to outlaw the research here in the US.

          • Howdy E. Grogan. Part 1.
            Well, I don’t like defending Fauci because I think he’s a fool. He may have, I do not know. But since President Clinton closed down COCOM (the Coordinating Committee for Multilateral Export Controls) in his first year in office, any country can get their hands on anything. Nothing is illegal.

          • Part 2.
            But to give you some perspective, in 2012 Dr. Ali Mohamed Zaki of Egypt sent a sample of a new corona virus to Ron Fouchier at the Erasmus Medical Center (EMC) in Rotterdam, the Netherlands. After sequencing it, the sample was sent to Scientific Director Dr. Frank Plummer of Canada’s National Microbiology Laboratory (NML) in Winnipeg in 2013. The Canadian lab grew up stocks of the virus and used it to assess diagnostic tests. In March 2019, a shipment of exceptionally virulent viruses (the new corona virus samples, along with the viruses Machupo, Junin, Rift Valley Fever, Crimean-Congo Hemorrhagic Fever and Hendra) from Canada’s NML ended up in Wuhan China. After an investigation of the unauthorized shipment, Dr. Xiangguo Qiu (and her husband Dr. Keding Cheng, also affiliated with the NML) who was the head of the Vaccine Development and Antiviral Therapies Section in the Special Pathogens Program at Canada’s NML, was expelled from Canada. No charges were filed.

          • Part 3.
            During their career, the couple brought in several students from a range of Chinese scientific facilities directly tied to China’s Biological Warfare Program, namely:
            Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun;
            Center for Disease Control and Prevention, Chengdu Military Region;
            Wuhan Institute of Virology, Chinese Academy of Sciences, Hubei;
            Institute of Microbiology, Chinese Academy of Sciences, Beijing;
            Dr. Xiangguo Qiu made at least five trips over the school year 2017-18 to the Wuhan National Biosafety Laboratory of the Chinese Academy of Sciences.
            So if Dr. Fauci did ship another sample of Covid, did he go to Canada to get it and was it before 2019?

      • Bill Gates is in public record saying on stage straight out that vaccines can be used to depopulate the planet

        • Howdy Annonymous. You are referring to the interview Bill Gates had with CNN’s Sanjay Gupta. He said, “….and then you would have all the tools to reduce childhood death, reduce population growth, and everything; the stability, the environment; benefits from that.” In other words, Gates actually believes that people would have fewer babies if the 3rd world had better health. That principle is nothing less than stupid, but I remember reading a UN report that took the position that well fed people, in the 3rd world, would have a lower birth rate. Which goes to show that having money and power doesn’t cure anyone from stupidity. So Bill Gates is stupid, but so is believing that vaccinations will somehow depopulate the planet. I mean think about it. If that were even remotely possible, China would be vaccinating their people right and left.

          • China IS vaxing their people right and left – and vaxes DO kill. in India, where Gates pushed his vaxes, many kids died. also, lots of folks got cancer from Salk vax for polio. look it up.

          • Howdy E. Grogan. Yes, vaccines do kill. And we all know that if we passed out baby aspirin to everyone in the US, people would die too. The question is scale. Do we offer a vaccine to 40 million people who are at significant risk of contracting a deadly disease, knowing that vaccine will kill 4,000 of them? Do we build the Golden Gate bridge, knowing that (statistically) 11 people will die building it; and even more people will die jumping off of it? I would be interested in knowing if a million or more people died or were sterilized in China from taking a vaccine. Especially if there is some documentation. But again, I agree with you. But it is a matter of scale.

    • Howdy Jimmy Robby Bobby. No offence meant, but that is such a silly thing to say. It’s a lot easier to create new strains in a laboratory test tube by using DNA cutting tools like CRISPR-Cas9 and CRISPR-Cas3. How do you think the Covid-19 virus was created in the first place?

    • vaccines have always been a small dose of the diseases that allow the body to develop immunity basically A safe dose Covid is EXPERIMENTAL because it’s the first vaccine that isnt that ,its a generic experiment and they’re excited by the POSSIBILITIES ..And they arent being open and honest about it in a way that the public really gets it ,what they’re really doing . They’re using scare tricks and prooagandas instead .Why ?

    • Theyre idiots volunteering for genetic experimentation Covid is not like other vaccines at all .Its jit a small bit of covid ,its a genetic experiment. That whole articles b/ s

      • Howdy Annonymous. People strapping themselves into a chair atop a rocket; or throwing themselves onto a live grenade to save their buddies are the same kind of “idiots”. It’s called bravery and self sacrifice. These people are heroes, and we will never even know their names. And yes, it is an experiment. They are trying to establish the parameters of the virus and the effectiveness of both natural and imposed immunity. Knowing this information will save many lives.

  1. As if bats invented these viruses What a load Always the sane always the opposite The great deceivers and Satans legions all in it together.As if viruses ” mutated ” or suddenly created themselves .All this rubbish to provide totally deceitful “findings ” to support their anti Christian evolution THEORY which they CANNOT prove is true because it’s not.

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